Search on: JOINASES, DNA 
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Descriptor English:   DNA Ligases 
Descriptor Spanish:   ADN Ligasas 
Descriptor Portuguese:   DNA Ligases 
Synonyms English:   T4 DNA Ligase
DNA Ligase, T4
Joinases, DNA
Ligase, T4 DNA
Ligases, DNA
Ligases, Polydeoxyribonucleotide
Synthetases, Polydeoxyribonucleotide
DNA Joinases
Polydeoxyribonucleotide Ligases
Polydeoxyribonucleotide Synthetases  
Tree Number:   D08.811.074.500
D08.811.464.754.600
Definition English:   Poly(deoxyribonucleotide):poly(deoxyribonucleotide)ligases. Enzymes that catalyze the joining of preformed deoxyribonucleotides in phosphodiester linkage during genetic processes during repair of a single-stranded break in duplex DNA. The class includes both EC 6.5.1.1 (ATP) and EC 6.5.1.2 (NAD). 
Indexing Annotation English:   do not confuse X ref POLYDEOXYRIBONUCLEOTIDE SYNTHETASES with X ref POLYRIBONUCLEOTIDE SYNTHETASE
History Note English:   98(77); for DNA LIGASES use POLYNUCLEOTIDE SYNTHETASES 1973-76 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   11522 
Unique Identifier:   D011088 

Occurrence in VHL:
 

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